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Canine & Feline Uveitis

Uveitis in dogs and cats is a painful, vision-threatening inflammation of the uveal tract, often secondary to systemic infections, immune-mediated disease, or trauma. Prompt recognition, identification of the underlying cause, and targeted anti-inflammatory therapy are essential for preserving vision and preventing complications.

Canine and Feline Uveitis


Definition:Inflammation of the uveal tract: iris, ciliary body, and choroid.


Causes (High-Yield):

  • Dogs: Tick-borne diseases (Ehrlichia, RMSF), blastomycosis, histoplasmosis, uveodermatologic syndrome, lens-induced (e.g. phacolytic/phacoclastic), trauma.

  • Cats: FIP, FeLV, FIV, Toxoplasma, fungal (esp. Cryptococcus), lymphoma.


Clinical Signs:

  • Blepharospasm, photophobia, epiphora

  • Aqueous flare (Tyndall effect)

  • Miosis, hypotony

  • Iris color change

  • Hyphema or hypopyon

  • Secondary glaucoma or cataracts (chronic)


Diagnosis:

  • Tonometry (↓ IOP early, ↑ if glaucoma develops)

  • Slit lamp exam

  • Fundic exam (if no hyphema)

  • CBC, chem, infectious disease testing (tick panel, FeLV/FIV, Toxo, FIP, fungal serology)


Treatment:

  • Topical steroids (e.g., prednisolone acetate)

  • Topical NSAIDs (e.g., diclofenac)

  • Systemic antibiotics or antifungals (if indicated)

  • Atropine to control pain and prevent synechiae

  • Treat underlying cause


Prognosis:Varies with cause and chronicity. Poor if secondary glaucoma develops.


NAVLE Tip:Know the infectious causes in cats, and that aqueous flare is a classic finding. Decreased IOP is a key early sign.


Further reading (veterinary source):

Merck Veterinary Manual: Anterior Uveitis in Small Animals


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