Insulinoma in Ferrets

Insulinoma in ferrets is a common endocrine disorder, especially in those older than 2-3 years. These functional tumors of the pancreatic beta cells are typically small and cause hypoglycemia due to excessive, uncontrolled insulin secretion. Clinical signs range from lethargy and weakness to seizures and coma. Diagnosis relies on clinical signs combined with low blood glucose levels and increased plasma insulin concentrations. Treatment options include both medical and surgical interventions. Medications like prednisone and diazoxide are used, and surgical options involve nodulectomy or partial pancreatectomy. The choice between medical and surgical treatment depends on various factors, including the number and location of pancreatic nodules.

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References:

Merck Veterinary Manual. Endocrine Disorders of Ferrets.