Drugs Prohibited for Extra Label use in food-producing animals

Drugs Prohibited for Extra Label use in food-producing animals

Extralabel drug use in veterinary species was made legal by the passage of the Animal Medicinal Drug Use Clarification Act (AMDUCA) in 1994. FDA can prohibit use of an entire class of drugs in selected animal species if the use of the drug or drug class presents a public health risk. 

The following drugs, families of drugs, and substances are prohibited for extralabel animal and human drug uses in food-producing animals. 

• Chloramphenicol

• Clenbuterol

• Diesthylstibestrol (DES)

• Dmetridazole

• Ipronidazole

• Other nitroimidazoles

• Furazolidone

• Nitrofurazone

• Sulfonamide drugs in lactating dairy cattle (except approved use of sulfadimethoxine, sulfabromomehtazine, and sulfaethoxypyridazine)

• Fluoroquinolones

• Glucopeptides

• Phenylbutazone in female dairy cattle 20 months of age or older

• Cephalosporins (not including cephapirin) in cattle, swine, chickens, or turkeys

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References:

• Jennifer L. Davis. Update on drugs prohibited from extralabel use in food animals. FARAD Digest. JAVMA, Vol 235, No 5, September 1, 2009. 

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Code of Federal Regulations 

Extralabel Drug Use in Animals

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Food Animal Residue Avoidance Databank

Prohibited and Restricted Drugs in Food Animals

Animal Medicinal Drug Use Clarification Act (AMDUCA)

U.S. Food & Drug Administration

The ins and outs of extra-label drug use in animals