

Estrus Phases in Dogs and Cats
Estrus Phases in Dogs and Cats
Estrus Cycle Phases:
Anestrus:
Characteristics: Ovarian inactivity, uterine involution, no attraction to males, small vulva, no discharge.
Cytology: Predominantly parabasal cells, occasional neutrophils.
Duration: 1–6 months.
Proestrus:
Characteristics: Attracts males but not receptive, serosanguineous discharge, mild vulvar enlargement.
Cytology: Shift from parabasal to superficial cells, presence of RBCs.
Duration: 3 days to 3 weeks (average 9 days).
Estrus:
Characteristics: Receptive to males, diminished discharge, peak vulvar edema.
Cytology: Predominantly superficial cells, decreasing RBCs.
Duration: 3 days to 3 weeks (average 9 days).
Diestrus:
Characteristics: Refractory to males, diminished discharge, resolution of vulvar edema.
Cytology: Reappearance of parabasal cells, frequent neutrophils.
Duration: 2–3 months (pregnancy or pseudo-pregnancy).
Cytological Changes and Their Meanings:
Parabasal Cells: Indicate anestrus or diestrus, low estrogen influence.
Intermediate Cells: Early estrogen influence, proestrus phase.
Superficial Cells: High estrogen influence, fertile period during estrus.
Assessment:
Vaginal Cytology: Essential for determining the stage of the cycle.
Hormonal Assays: Progesterone and LH testing to time breeding accurately.
Treatment:
Hormonal Management: Progesterone levels for ovulation timing.
Antimicrobials: For infections if present.
For more details, visit the Merck Veterinary Manual.





